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| | #256 (permalink) |
| Registered User Join Date: May 2002
Posts: 1,505
+1 Internets | I have a bottle of 500 .5mg alprozalam sitting beside me. Legitimate though. But I'm rather aware of the risks. The worst thing I did was give myself a roofie by mistake one time (misjudged time, and drank) What you described sounds more like E. Not that I had any experience with illicit drugs in my youth, no sir. edit: he would've been fine if he stuck to xanax, you can take large amounts, but as long as you don't swallow a bottle you're fine. He took three different BZDs, with differential binding profiles/affinities to each receptor subtype. More, alprozolam and diazepam share the same metabolic elimination pathway (and therefore, you extend the drug half life and bioavailability for each). Moreover, xanax is fast acting and strong, but short duration; valium long duration, but not as strong; temazepam long duration and strong effect. This is ignoring the OTC sleep aid and the two powerful narcotics (which may also involve cytochrome p450, which would have made everything even more complicated, and let's hope he didn't consume any grapefruit). You either need to be a complete addict, a complete wreck, or have a death wish, or all three, to take what he did simultaneously. I'm betting the latter two, with possibly the former, which means he wasn't just a "junkie" but a disturbed fellow. RIP. Last edited by Schatze : 02-08-2008 at 01:14 AM. |
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| | #257 (permalink) | |
| Registered User Join Date: Jun 2005
Posts: 609
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Ledger was a druggie, just so happens he wasn't a very smart one and accidentally killed himself. | |
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| | #259 (permalink) |
| Registered User Join Date: May 2002
Posts: 1,505
+1 Internets | Actually, Rush did rail quite a bit against addicts and junkies. When the oxycontin story broke, I remember seeing quotes and excerpts filtered from the years of accumulated verbal excrement he'd spewed to show how hypocritical he was. edit; Is there anywhere where it says if Heath Ledger had actually been prescribed these drugs, or if he'd gotten them through illicit channels? The initial reports just mentioned OTC sleep pills being found on site. Last edited by Schatze : 02-08-2008 at 02:38 AM. |
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| | #262 (permalink) | |
| Come on inside, n' meet the missus Join Date: Oct 2002 Location: In self-exile
Posts: 1,998
+7 Internets | uh...since when are they making more Spiderman movies?
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| | #264 (permalink) |
| Grand High Poobah Join Date: Aug 2002 Location: Philadelphia
Posts: 3,755
+6 Internets | I thought I had read some time ago that they had wanted to do six films. |
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| | #265 (permalink) | |
| Come on inside, n' meet the missus Join Date: Oct 2002 Location: In self-exile
Posts: 1,998
+7 Internets | You got a source for that? Sam Raimi said he would like to, but none of the actors want to.
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| | #267 (permalink) | |
| Come on inside, n' meet the missus Join Date: Oct 2002 Location: In self-exile
Posts: 1,998
+7 Internets | Yeah, I just read that. It's over a year old, and from before the release of the steaming pile that was the third movie. We'll see if it ever happens, but I doubt it.
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| | #269 (permalink) | |
| The Undead Shaman Join Date: Jun 2006 Location: NYC
Posts: 3,528
| Quote:
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