[Tuco]

I've seen a number of videos of people replacing a mouse/keyboard with wii controllers, and everything I've seen has the practical equivalence of someone showing me a video of them using a mouse with their foot.

I don't think it'll have real use until a game (for the PC at least) comes out with more complex actions that can't be realized with keys. For example, realistic 'swordplay' with true translation of Wii-mote (or other motion sensory controller) and a sword. The example I saw on Wii simply had a half dozen or whatever sword attacks that would be played dependent on the motion of the wii, rather than using the wii as an actual sword.